From: Nature Alert [Nature@ealerts.nature.com]
Sent: 08 November 2006 11:20 PM
To: Muraya, Peter (ICRAF-ILRI)
Subject: Nature 9 November 2006 Volume 444 Number 7116, pp123-242
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TABLE OF CONTENTS


Volume 444 Number 7116 123-242 This alert is sponsored by Biorad

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In this issue
Authors
Editorials
Research Highlights
News
Business
News Features
Correspondence
Commentaries
Books and Arts
News and Views
Brief Communications
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Articles
Letters
Naturejobs
Futures

Also this week
Editor's summary
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Authors

Top
Making the paper: Ya Ha pxiii
Understanding how proteases cut inside the cell membrane.
10.1038/7116xiiia
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Abstractions pxiii
10.1038/7116xiiib
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Key Collaboration pxiii
10.1038/7116xiiic
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Editorials

Top
Another one bites the dust p123
The hazards of seeking to implement reforms at universities with outstanding reputations have been demonstrated once again, this time in Switzerland.
10.1038/444123a
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Correction or retraction? p123
Errors reported in this issue by authors of a Nature paper pose a dilemma about trust.
10.1038/444123b
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Smart but lightweight p124
An imaginative innovation policy in Britain continues to be under-resourced.
10.1038/444124a
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Research Highlights

Top
Research highlights p126
10.1038/444126a
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News

Top
Telescope is no longer dish of the day p128
Arecibo in the firing line as US observatories face cuts.
Heidi Ledford
10.1038/444128a
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Data handling causes image problem for top lab p129
Correction to 1993 paper gets physicists talking.
Geoff Brumfiel
10.1038/444129a
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It's the junk that makes us human p130
'Non-coding' DNA may organize brain cell connections.
Erika Check
10.1038/444130a
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Faculty forces president to quit Swiss role p130
Leading European university in turmoil.
Alison Abbott
10.1038/444130b
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Power up your memory bank p133
A stimulating night's sleep improves recall.
Kerri Smith
10.1038/444133a
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Telling the time p134
Geochronologists are pinning down dates in deep time better than ever before. Rex Dalton talks to the experts who are redrawing the details of Earth history.
10.1038/444134a
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Sidelines p135
10.1038/444135a
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News in brief p136
10.1038/444136a
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Business

Top
A breed apart p137
The US Food and Drug Administration may soon approve the use of cloned livestock for food. But regulatory roadblocks aren't the only thing keeping clones off the menu, as Heidi Ledford reports.
10.1038/444137a
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News Features

Top
Radio astronomy: Dutch courage p138
Most astronomers head for remote mountain-tops or deserts to study the cosmos. Jenny Hogan meets a confident team set up on a patch of farmland in a crowded corner of mainland Europe.
10.1038/444138a
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Infant pain: Does it hurt? p143
Working out whether premature babies feel pain has important implications for child development, says Jane Qiu.
10.1038/444143a
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Correspondence

Top
An open letter to Colonel Muammar al-Gaddafi p146
Richard J. Roberts and 113 fellow Nobel Laureates
10.1038/444146a
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Don't forget the steps that led physics to where it is p146
Antonino Zichichi
10.1038/444146b
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Biodiversity definitions vary within the discipline p146
Alison Holt
10.1038/444146c
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US scorn for treaties hasn't improved nuclear security p146
Sebastian Raupach
10.1038/444146d
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Books and Arts

Top
One culture? p147
We can gain a clearer picture of visual representation by crossing the divide between art and science.
Bart Kahr reviews Seen | Unseen: Art, Science and Intuition from Leonardo to the Hubble Telescope by Martin Kemp
10.1038/444147a
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See also: Editor's summary

Exhibition: Sowing the seeds p148
Simon Mawer reviews Gregor Mendel: Planting the Seeds of Genetics
10.1038/444148a
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Correction p148
10.1038/444148b
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Exhibition: The ballerina within p149
Laura Spinney reviews Picasso XRAYS
10.1038/444149a
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Easing the pain p149
John Carmody reviews The Worst of Evils: The Fight Against Pain by Thomas Dormandy
10.1038/444149b
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News and Views

Top
Cell biology: A clean energy programme p151
Mitochondria supply cells with energy, but in the process produce potentially damaging oxidants. It seems that a protein required to produce new mitochondria also protects against the resulting oxidative damage.
Toren Finkel
10.1038/444151a
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Climate change: The south-north connection p152
A new ice-core record from Antarctica provides the best evidence yet of a link between climate in the northern and southern polar regions that operates through changes in ocean circulation.
Eric J. Steig
10.1038/444152a
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See also: Editor's summary

Structural biology: Enzyme theory holds water p153
Intramembrane proteases have attracted much attention because of their biological and medical value. The first crystal structure of one of these enzymes begins to solve the mystery of how they work.
Matthew Freeman
10.1038/nature05305
Full Text | PDF
See also: Editor's summary

Neurobiology: Right timing for retina repair p156
Transplants of photoreceptor cells offer hope for treating retinal disease. But getting the cells to make the right connections with the brain has been problematic. It seems the developmental stage of the cells may be the key.
Thomas A. Reh
10.1038/444156a
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See also: Editor's summary

Physiology: Channelled pain p156
Lesley Anson
10.1038/444156b
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See also: Editor's summary

Astronomy: A troupe of near dwarfs p158
Faint satellite galaxies of the Milky Way are being discovered that are dimmer than some of the Milky Way's star clusters. This finding poses a fundamental question: what are galaxies?
Sidney van den Bergh
10.1038/444157a
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50 & 100 Years Ago p159
10.1038/444159b
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Immunology: Exposure of an executioner p159
The complement C3 protein binds to pathogens, singling them out for execution by the immune system. Structural studies show how the chemical group responsible for this binding is exposed on activation.
Michael Carroll
10.1038/nature05307
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Quantum physics: Information on heat p161
There is a fundamental quantum limit to heat flow, just as there is to electric current. This limit is independent of what carries the heat, and could also have a role in an unexpected quarter: information theory.
Keith Schwab
10.1038/444161a
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Earth science: Isotopic hide and seek p162
Isotopes formed by the decay of radioactive nuclei provide evidence of how Earth was shaped in its infancy. But some decay products seem to be hidden - a finding that will revitalize a debate about Earth's interior.
Francis Albarede
10.1038/444162a
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Brief Communications

Top
Mechanoluminescence: Light from sonication of crystal slurries p163
Light flashes sparked by acoustic shock waves far outshine those created by manual crushing.
Nathan C. Eddingsaas and Kenneth S. Suslick
10.1038/444163a
First paragraph | Full Text | PDF

Human immunodeficiency viruses: SIV infection in wild gorillas p164
Fran Van Heuverswyn et al.
10.1038/444164a
First paragraph | Full Text | PDF
See also: Editor's summary


Articles

Top
Great Himalayan earthquakes and the Tibetan plateau p165
Nicole Feldl and Roger Bilham
10.1038/nature05199
Abstract | Full Text | PDF
See also: Editor's summary

Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia p171
A study of the duplicated genes in Paramecium tetraurelia suggests that after whole-genome duplication events, many duplicated genes are not able to immediately functionally diverge, because dosage constraints act on them. These dosage constraints also prevent loss of many duplicated genes after whole genome duplications.
Jean-Marc Aury et al.
10.1038/nature05230
Abstract | Full Text | PDF
See also: Editor's summary

Crystal structure of a rhomboid family intramembrane protease p179
The first description of the crystal structure of an intramembrane protease suggests a model where the substrate enters through a gated opening, unfolds, and becomes cleaved inside the membrane-embedded protease.
Yongcheng Wang, Yingjiu Zhang and Ya Ha
10.1038/nature05255
Abstract | Full Text | PDF
See also: Editor's summary | News and Views by Freeman


Letters

Top
Lunar activity from recent gas release p184
Patches of the lunar regolith in the Ina structure were recently removed, with the number of superimposed small craters and the 'freshness' of the regolith indicating that features within this structure must be as young as 10 million years. It is suggested that these result from recent, episodic out-gassing from deep within the Moon.
Peter H. Schultz, Matthew I. Staid and Carle M. Pieters
10.1038/nature05303
First paragraph | Full Text | PDF
See also: Editor's summary

Single-mode heat conduction by photons p187
A clever experiment that makes use of two metallic islands connected by superconducting leads now confirms that thermal conduction by photons is limited by the same quantum value. Although the result is mainly of fundamental importance, there are implications for the design of bolometers, detectors of far-infrared light that are used in astrophysical studies, and electronic micro-refrigerators.
Matthias Meschke, Wiebke Guichard and Jukka P. Pekola
10.1038/nature05276
First paragraph | Full Text | PDF
See also: News and Views by Schwab

Boundary lubrication under water p191
Wuge H. Briscoe et al.
10.1038/nature05196
First paragraph | Full Text | PDF
See also: Editor's summary

One-to-one coupling of glacial climate variability in Greenland and Antarctica p195
EPICA Community Members
10.1038/nature05301
First paragraph | Full Text | PDF
See also: Editor's summary | News and Views by Steig

An exceptional Devonian fish from Australia sheds light on tetrapod origins p199
John A. Long et al.
10.1038/nature05243
First paragraph | Full Text | PDF
See also: Editor's summary

Retinal repair by transplantation of photoreceptor precursors p203
R. E. MacLaren et al.
10.1038/nature05161
First paragraph | Full Text | PDF
See also: Editor's summary | News and Views by Reh

Spider toxins activate the capsaicin receptor to produce inflammatory pain p208
Jan Siemens et al.
10.1038/nature05285
First paragraph | Full Text | PDF
See also: Editor's summary | News and Views by Anson

Structure of C3b reveals conformational changes that underlie complement activity p213
Bert J. C. Janssen et al.
10.1038/nature05172
First paragraph | Full Text | PDF
See also: Editor's summary | News and Views by Carroll

Structure of C3b in complex with CRIg gives insights into regulation of complement activation p217
Christian Wiesmann et al.
10.1038/nature05263
First paragraph | Full Text | PDF
See also: Editor's summary | News and Views by Carroll

The structure of complement C3b provides insights into complement activation and regulation p221
A. Abdul Ajees et al.
10.1038/nature05258
First paragraph | Full Text | PDF
See also: Editor's summary | News and Views by Carroll

Wza the translocon for E. coli capsular polysaccharides defines a new class of membrane protein p226
The X-ray crystal structure of the 340-kDa octamer of Wza, essential for group 1 capsule export in Escherichia coli, is determined. A large portion of Wza is located in the periplasm and the protein contains a large central cavity, through which capsular polysaccharides are translocated.
Changjiang Dong et al.
10.1038/nature05267
First paragraph | Full Text | PDF
See also: Editor's summary

A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling p230
Adam Friedman and Norbert Perrimon
10.1038/nature05280
First paragraph | Full Text | PDF


Corrigenda

Top
Atomic-resolution chemical analysis using a scanning transmission electron microscope p235
N. D. Browning, M. F. Chisholm and S. J. Pennycook
10.1038/nature05262
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Earthquakes triggered by silent slip events on Kilauea volcano, Hawaii p235
Paul Segall et al.
10.1038/nature05297
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Erratum

Top
Centrosome polarization delivers secretory granules to the immunological synapse p236
Jane C. Stinchcombe et al.
10.1038/nature05299
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Naturejobs

Top
Prospect
Prospects p237
Paul Smaglik
10.1038/nj7116-137a
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Special report
Closing the deal p238
Sales and marketing jobs at pharmaceutical companies offer the opportunity to combine science with social skills and creative flair. Hannah Hoag investigates the pitch.
10.1038/444238a
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Career Views
Georgina Mace, director, Centre for Population Biology, Imperial College London, UK p240
Georgina Mace addresses conservation efforts as head of a population-biology centre.
Virginia Gewin

10.1038/nj7116-240a
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The view from Russia p240
Russian science is slowly adapting to political change.
Monya Baker
10.1038/nj7116-240b
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The path to a PhD p240
How I fell in love with plants on the way to a PhD.
Mhairi Dupr
10.1038/nj7116-240c
Full Text | PDF


Futures

Top
Making the sale p242
Give 'em the easy choice.
Fredric Heeren
10.1038/444242a
Full Text | PDF


Advance Online Publication

Top
8 November 2006
LETTERS

Influence of the thalamus on spatial visual processing in frontal cortex
Marc A. Sommer and Robert H. Wurtz

doi: 10.1038/nature05279
Abstract | Full Text | PDF | Supplementary information

A protein interaction network for pluripotency of embryonic stem cells
Jianlong Wang, Sridhar Rao, Jianlin Chu, Xiaohua Shen, Dana N. Levasseur, Thorold W. Theunissen and Stuart H. Orkin

doi: 10.1038/nature05284
First Paragraph | Full Text | PDF | Supplementary information

5th November 2006
LETTERS

Boosting slow oscillations during sleep potentiates memory
Lisa Marshall, Halla Helgadttir, Matthias Mlle and Jan Born

doi: 10.1038/nature05278
Abstract | Full Text | PDF | Supplementary information


In vivo enhancer analysis of human conserved non-coding sequences
Len A. Pennacchio, Nadav Ahituv, Alan M. Moses, Shyam Prabhakar, Marcelo A. Nobrega, Malak Shoukry, Simon Minovitsky, Inna Dubchak, Amy Holt, Keith D. Lewis, Ingrid Plajzer-Frick, Jennifer Akiyama, Sarah De Val, Veena Afzal, Brian L. Black, Olivier Couronne, Michael B. Eisen, Axel Visel and Edward M. Rubin

doi: 10.1038/nature05295
Abstract | Full Text | PDF | Supplementary information


Self-incompatibility in Papaver targets soluble inorganic pyrophosphatases in pollen
Barend H. J. de Graaf, Jason J. Rudd, Michael J. Wheeler, Ruth M. Perry, Elizabeth M. Bell, Kim Osman, F. Christopher H. Franklin and Vernonica E. Franklin-Tong

doi: 10.1038/nature05311
Abstract | Full Text | PDF | Supplementary information

NEWS AND VIEWS
Neuroscience: A memory boost while you sleep
Robert Stickgold

doi: 10.1038/nature05309
Abstract | Full Text | PDF | Supplementary information


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